New and emerging immunosuppressive agents for kidney transplantation
نویسندگان
چکیده
منابع مشابه
Immunosuppressive drugs for kidney transplantation.
N Engl J Med 2004;351:2715-29. Copyright © 2004 Massachusetts Medical Society. he central issue in organ transplantation remains suppression of allograft rejection. Thus, development of immunosuppressive drugs is the key to successful allograft function. Immunosuppressive agents are used for induction (intense immunosuppression in the initial days after transplantation), maintenance, and revers...
متن کاملState of immunosuppressive agents in organ transplantation.
TRANSPLANT A nON has been built on the foundation of using drug thera.py to nonspecifically suppress the recipient immune response. Failure to achieve adequate immunosuppression is associated with a high incidence of graft loss from rejection. The present goal of immunosuppressive regimens is to suppress the immune response to the allograft while preserving sufficient immunity to avoid opportun...
متن کاملModern Immunosuppressive Therapy in Kidney Transplantation
Immunosuppressive therapy is a key component for successful kidney transplantation. It is commonly believed that more intensive immunosuppression is needed initially to prevent rejection episodes and less immunosuppression is subsequently maintained to minimize the overall risk of infection and malignancy. The selection of drugs should be guided by a comprehensive assessment of the immunologic ...
متن کاملNew immunosuppressive regimens in lung transplantation.
Survival after lung transplantation is less than 50% after 5 yrs and is limited by infection and obliterative bronchiolitis. There is, therefore, a need for new immunosuppressive regimens if we are to attempt to improve long-term survival. Several trials in lung transplantation of new immunosuppressive agents are in the planning stages. In this article, we review the experience with a new monoc...
متن کاملNew immunosuppressive drugs in heart transplantation
Only a few randomized clinical trials have been performed so far in heart transplant recipients, mainly because of the relatively small number of heart transplants performed worldwide each year. The main focus of the few controlled trials that have been completed has been the prevention and treatment of heart allograft rejection. In the area of pharmacologic immunosuppression, both biological a...
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ژورنال
عنوان ژورنال: Dialysis & Transplantation
سال: 2011
ISSN: 0090-2934
DOI: 10.1002/dat.20532